Estimated achievement difficulty: 2
Estimated time for 1000: 5-6 hours.
Minimum playthroughs: 1
Missable achievements: Reluctant Hero
Glitched achievements: Steel Cannibal
Offline: All
Online: None
The achievements for this game are a piece of cake, if you know what to do and should get all 200 points with one playthrough. The only one that can be missed is Reluctant Hero. Just refuse to join Gabe and Tycho 5 times in a row until this one unlocks. You don't need all the robot parts to upgrade the weapons, because you will have 610 left. But I would say kill all the robots so you will get to 30 in time.
The Steel Cannibal achievement is also glitched and sometimes won't unlock, so you better save before the last upgrade or you have to do the whole game again. A patch was recently released, but is still unknown if it fixed the glitch.
For all the other non story related achievements you can do them all before entering the last area at the worlds fair. So you can do Lab Assistant and Pervert if you load a save state that is before the ending.
[x360a would like to thank L0cke for this road map]